Without prompt and effective
treatment, SHPT becomes:
- Progressively more severe1,9,11,12
- Increasingly unresponsive to medical treatment as the hyperplastic parathyroid glands become less sensitive to calcium and vitamin D hormone signalling1,4,13,14
EARLY DIAGNOSIS AND TREATMENT ARE
CRUCIAL IN THE MANAGEMENT OF SHPT1,9,10
1,25(OH)2D: 1,25-dihydroxyvitamin D; CKD: chronic kidney disease; FGF-23: fibroblast growth factor-23; PTH: parathyroid hormone; SHPT: secondary hyperparathyroidism.