In CKD stages 3–5, progressively higher 25(OH)D levels are:20
- Associated with lower PTH concentrations
- Not associated with increased rates of hypercalcaemia or hyperphosphataemia
The effect of 25(OH)D to reduce PTH does not decrease until 25(OH)D levels of 42–48 ng/mL (105–120 nmol/L).20/sites/g/files/brlbcj1106/files/2020-06/Bricks_cutted-min.png
TO CONTROL SHPT, A 25(OH)D LEVEL OF
42-48 NG/ML (105-120 NMOL/L) IS REQUIRED20
25(OH)D: 25-hydroxyvitamin D; CKD: chronic kidney disease; PTH: parathyroid hormone; SHPT: secondary hyperparathyroidism.