HCP check
HCP check

Welcome to SHPT Challenges

This website contains information about secondary hyperparathyroidism (SHPT). It is intended to provide information to an international audience outside of the USA.

You are now leaving our website and heading to a third-party website that we do not operate. We are not responsible for the content of the third-party website. You are advised to review its privacy policy as it may differ from ours.

Are you sure you want to leave?

Confirm

Cancel

Loss of mineral

homeostasis due to renal

failure leads to:3,4

  • Parathyroid gland hyperplasia
  • Bone and cardiovascular complications
/sites/g/files/brlbcj1106/files/2020-03/Background_Bricks_1400-min-min.png

SHPT IS A MALADAPTIVE RESPONSE TO DISRUPTED MINERAL AND VITAMIN D HOMEOSTASIS DUE TO RENAL FUNCTION DECLINE3

/sites/g/files/brlbcj1106/files/2020-06/Pathogenesis_Graph-min.png

1,25(OH)2D: 1,25-dihydroxyvitamin D; 25(OH)D: 25-hydroxyvitamin D; CKD: chronic kidney disease; FGF-23: fibroblast growth factor-23; PO: phosphate;

PTH: parathyroid hormone; sCa: serum calcium; SHPT: secondary hyperparathyroidism; sPO: serum phosphate.